Centro Histórico: The historic heart of Mexico City, Centro Histórico is where many major landmarks are located, including the Zócalo, the Metropolitan Cathedral, and the National Palace. It’s a bustling area with museums, shops, restaurants, and street vendors. While generally safe during the day, some streets can feel less secure at night, so it’s best to stick to the main areas and avoid side streets after dark.
Roma: Known for its bohemian vibe, Roma is filled with art galleries, vintage shops, cafes, and hip restaurants. Roma Norte, in particular, is popular with young professionals and tourists, while Roma Sur is quieter and more residential. Although the area is generally safe, some visitors may want to be more cautious late at night.
Condesa: Bordering Roma, Condesa has a similar hip, artistic atmosphere with tree-lined streets, beautiful parks (like Parque México and Parque España), and a vibrant dining scene. It’s known for a high concentration of bars, which make it lively at night, though fairly safe.
Polanco: Often considered one of the most upscale neighborhoods, Polanco is known for luxury shopping along Avenida Presidente Masaryk, fine dining, embassies, and large green spaces like Chapultepec Park. It’s safe and popular among locals and expats alike, and is home to some of the city’s best museums, like Museo Soumaya and the National Museum of Anthropology.
Coyoacán: This charming, artsy neighborhood has a small-town feel with plazas, colorful colonial houses, markets, and the Frida Kahlo Museum. Coyoacán is known for its traditional vibe and is generally very safe, attracting locals and tourists alike, especially on weekends.
Santa Fe: A newer district known for skyscrapers, business centers, and luxury shopping malls like Centro Santa Fe, the largest mall in Latin America. Santa Fe caters mostly to business professionals and is safe, though it lacks much of the charm and cultural appeal of other neighborhoods.
San Ángel: Known for its colonial architecture, cobblestone streets, and Bazar Sábado art market, San Ángel is a peaceful, residential area with historical charm. It’s a safe place to explore, particularly for art lovers and those looking to experience more traditional aspects of Mexican culture.
Juárez: This central neighborhood includes Zona Rosa, a vibrant LGBTQ+ district with bars, clubs, and shops catering to the community. Juárez is lively and culturally diverse, generally safe, though Zona Rosa can be busy and attract crowds at night.
Tlatelolco: Tlatelolco is a neighborhood with significant historical relevance, known for the Plaza de las Tres Culturas, where Aztec, colonial, and modern structures coexist. While safe to visit during the day, some parts can be unsafe at night, so visitors should exercise caution and stick to main areas.
Iztapalapa: Known as one of Mexico City's largest and most densely populated areas, Iztapalapa has areas with significant economic challenges. While it has cultural events like the annual Passion Play, it’s generally not recommended for tourists, as some areas have higher crime rates.
Tepito: Tepito is one of the city's oldest neighborhoods, known for its massive street market offering almost anything. However, it's also one of the most dangerous neighborhoods in Mexico City, with high rates of crime. This area is best avoided by tourists, especially without a local guide.
Doctores: Known for its traditional architecture, Doctores has some affordable food markets but is not particularly safe, especially at night. The area is generally advised against for tourists, as it has a reputation for crime.